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The effects of cannabis extract rich in CBD on the basis of a scientific study


Inflammation and pain have accompanied everyday life since ancient times. During that time, a number of medications and medical procedures have been developed to fight inflammation and pain, however, many of these drugs have serious side effects. For thousands of years, cannabis has been used in various forms as an effective combatant in the fight against pain. [2] - [4]

CBD or Cannabidiol, as the main component of cannabis, has proved to be a strong anti-inflammatory and anti-asthma drug without psychotropic effects. However, when administered in the form of a pure isolate, a response with a bell-shaped curve was observed which limits its clinical use.

In 2015, the results of a scientific study [1], which focused on the use of cannabis extract, namely Cannabis sativa L., clone 202 (hereinafter referred to as extract), was used instead of the pure CBD isolate. Anti-inflammatory and pain-relieving effects were investigated. It has been shown that with increasing doses of the extract, the reaction to them increases. This plant extract makes it ideal for clinical use.

Since cannabis extract has strong anti-inflammatory effects, as described above, it was important to compare its effects with commercial anti-inflammatory drugs in the study [1]. For the purpose of this test, the researchers chose two drugs: Tramadol, a powerful analgesic, and Aspirin; known as a non-steroidal anti-inflammatory drug and also a painkiller. While Aspirin had a mild effect on the swelling of the inflamed paws in the mice tested, Tramadol had almost no effect at all. In contrast, cannabis extract significantly prevented paw swelling to a much greater extent than Aspirin. The result of this test has shown that cannabis extract is superior to Tramadol and Aspirin with excellent anti-inflammatory properties.

The outcome of the study is the recommendation of its authors to use cannabis extract to treat various inflammatory diseases.

Details of the scientific study can be found here.

[1] Galliby, R., Yekhtin, Z., Hanuš, L.O. (2015) Overcoming the Bell-Shaped Dose Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Scientific Reseach Publishing, 75-85. More info

[2] Hazekamp, A., Ware, M.A., Muller-Vahl, K.R., Abrams, D. and Grotenhermen, F. (2013) The Medicinal Use of Can- nabis and Cannabinoids—An International Cross-Sectional Survey on Administration Forms. Journal of Psychoactive Drugs, 45, 199-210. More info

[3] Mechoulam, R. (2012) Cannabis—A Valuable Drug That Deserves Better Treatment. Mayo Clinic Proceedings, 87, 107-109. More info

[4] Greydanus, D.E., Hawver, E.K., Greydanus, M.M. and Merrick, J. (2013) Marijuana: Current Concepts. Frontiers in Public Health, 1, 42. More info

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